Clinical Research in Cerebral and Pulse Oximetry
Nonin Medical is committed to investments in clinical research and education to improve patient care and safety. By partnering with leading clinicians and institutions in rigorous, scientific exploration of our technologies, Nonin aims to contribute to the general knowledge of NIRS tissue oximetry. Such collaborations allow for the advancement of clinical practice and technology solutions that will meet the unique and sometimes extraordinary needs of clinicians.
EQUANOX Clinical Resources
- Apostolidou I, Morrissette G, Sarwar MF, et al. Cerebral oximetry during cardiac surgery: The association between cerebral oxygen saturation and perioperative patient variables.J Cardiothorac Vasc Anesth. 2012 Dec;26(6):1015-21
- Apostolidou I, Morrissette G, Sarwar M, et al. Clinical Assessment of Cerebral Oximetry during Cardiovascular Surgery.Society of Cardiovascular Anesthesiologists. Boston, MA. May 1, 2012. Poster session.
- Aronson S, Lane K, Clemmons K, Waweru P. Incidence and characteristics of cerebral oximetry and cognitive dysfunction during the post-operative period during cardiac surgery. Society of Cardiovascular Anesthesiologists. Boston, MA. April 30, 2012. Poster session.
- Cote K. Cerebral oximetry: Is it really a no brainer?American Society of Extracorporeal Technology. Orlando, FL. March 30, 2012. Poster session.
- Deng Y, Pisklak P, Pan W. Successful Use of Near Infrared Spectroscopy (NIRS) During Three Hours of Hypothermic Circulatory Arrest for Aortic Arch Repair.Society of Cardiovascular Anesthesiology. Society of Cardiovascular Anesthesiologists. Boston, MA. April 29, 2012. Poster presentation.
- MacLeod DB, Ikeda K, Vacchiano C, et al. Development and Validation of a Cerebral Oximeter Capable of Absolute Accuracy.Journal of Cardiothoracic and Vascular Anesthesia, 2012 Dec; 26(6):1007-14.
- Abicht JM, Schmitz C, Bauer A, Wolf M, Christ F. Cerebral oximetry monitoring during transapical aortic valve replacement. American Society of Anesthesiologists Annual Meeting. San Diego, CA. October 16, 2010. Poster session.
- Abicht J, Schmitz C, Sodian R, Wolf M, Nikolaou K, Christ F. Cerebral oximetry monitoring during transapical aortic valve replacement. Thorac Cardiovascular Surg. 2010; 58.
- Fischer GW, Silvay G. Cerebral oximetry in cardiac and major vascular surgery, HSR Proceedings in intensive Care and Cardiovascular Anesthesia. 2010; 2:249 - 256.
Orthopedic Beach Chair
- Koh JL, et al. Cerebral oxygenation in the beach chair position; a prospective study on the effect of general anesthesia compared with regional anesthesia and sedation. J Should Elbow Surg 2013;epub
- Rohrbaugh M, et al. Outcomes of shoulder surgery in the sitting position with interscalene nerve block. Reg Anesth Pain Med 2013;38;28-33
- Salazar D, et al. Cerebral desaturation events during shoulder arthroscopy in the beach chair position: Patient risk factors and neurocognitive effects. J Shoulder Elbow Surg 2013; Feb 15pii:S(1058-2746(13)00012-8
- Salazar D. Cerebral desaturation events during shoulder arthroscopy in the beach chair position; patient factors and neurocognitive events. J Shoulder Elbow Surg 2013;epub
- Salazar D, et al. Cerebral desaturation during shoulder arthroscospy; a prospective observational study. Clin Orthop Relat Res 2013;epub
- Shear T, Murphy G. Impact of the Beach Chair Position on Cerebral Perfusion: What Do We Know So Far? Clin Orthop Relat Res 2013;epub
- Soeding PF, et al. Effect of phenylephrine on the haemodynamic state and cerebral oxygen saturation during anesthesia in the upright position. Br J Anesth 2013;epub
- Zeidan A, Bluwi M, Elshamaa K. Postoperative brain stroke after shoulder arthroscopy in the lateral decubitus position. J Stroke Cerebrovasc Dis 2013;epub
- Lee JH, et al. Effects of beach chair position and induced hypotension on cerebral oxygen saturation in patients ucontentergoing arthroscopic shoulder surgery. J Arthro and Rel Surg 2011;27;889-894
- Rains DD, Rook GA and Wahl CJ. Pathomechanisms and complications related to patient positioning and anesthesia during shoulder arthroscopy. J Arthro and Rel Surg 2011;27;532-541
- Soeding PF, et al. The effect of the sitting upright or beach chair positon on cerebral blood flow during anesthesia for shoulder surgery. Anaesth Int Care 2011;39;440-448
- YaDeau JT, et al. Stroke, regional anesthesia in the sitting position and hypotension. Reg Anesth Pain Med 2011;36;430-435
- Fischer GW, et al. The use of cerebral oximetry as a monitor of the adequacy of cerebral perfusion in a patient undergoing shoulder surgery. Pain Pract 2009;9;304-307
- Friedman D, et al. Prevalence of Cerebrovascular Events During Shoulder Surgery and Association With Patient Position Orthopedics April 2009; Vol 32 Issue 4
- Mazzon D, et al. Beach chair position, general anesthesia and deliberated hypotension during shoulder surgery; a dangerous combination. Minerva Anesth 2009;75;281-282
- Peruto CM, Cicotti MG, Cohen SB. Shoulder arthroscopy positioning; lateral decubitus versus beach chair. J Arthroscop and Rel Surg 2009;25;891-896
- Choi SH, et al. Nitroglycerin and nicardipine induced hypotension does not affect cerebral oxygen saturation and postoperative cognitive function. J Oral Maxillofac Surg 2008;66;2104-2109
- Papadonikolakis A, et al. Avoiding catastrophic complications of stroke and death related to shoulder surgery in the sitting position. J Arthrosc and Rel Surg 2008;24;481-482
- Pohl A, Cullen DJ. Cerebral ischemia during shoulder surgery in the upright position; a case series. J Clin Anesth 2005;17;463-469
- Bhatti MT, Enneking FK. Visual Loss and Opthalmoplegia After Shoulder Surgery. Anesth Analg 2003;96;899-902
- Endoh H, et al. The influence of nicardipine, nitroglycerin- and prostaglandin E1 induced hypotension on cerebral pressure autoregulation. Anesth Analg 2002;94;169-173
- Brown RH, Schauble JF, Miller NR. Anemia and hypotension as contributors to perioperative loss of vision. Anesth 1994;80;222-226
- Kreeger R, Ramamoorthy C, Nicolson S, et al. A Novel Device to Measure Cerebral Oxygen Saturation in Neonates, Infants and Children.Society for Pediatric Anesthesia. Tampa, FL. February 25, 2012. Poster presentation.
- Kreeger R, Ramamoorthy C, Nicolson S, Ames W. Development and Evaluation of a Near Infrared Cerebral Oximeter for Congenital Heart Disease.Society of Thoracic Surgeons. Fort Lauderdale, FL. January 30, 2012. Poster presentation.
- Kreeger RN, Ramamoorthy C, Nicolson SC, et al. Evaluation of Pediatric Near-Infrared Cerebral Oximeter for Cardiac Disease. Annals Thoracic Surgery. 2012;94:1527-33.
- Ahn A, Yang J, Inigo-Santiago L, Parnia S. A feasibility study of cerebral oximetry monitoring during the post-resuscitation period in comatose patients following cardiac arrest. Resuscitation. 2014 Apr;85(4).
- Genbrugge C, Dens J, Meex Msc I, et al. Mean initial cerebral saturation (rSO2) during advanced life support (ALS) in out-of hospital cardiac arrest (OHCA) patients, predictor of survival? Poster Presented at the Belgian Society of Emergency and Disaster Medicine, 2014.
- Parnia S, Nasir A, Ahn A, Malik H, et al. A feasibility study of cerebral oximetry during in-hospital mechanical and manual cardiopulmonary resuscitation. Crit Care Med. 2014 Apr;42(4).
- Singer AJ, Ahn A, Inigo-Santiago LA, et al. Cerebral oximetry levels during CPR are associated with return of spontaneous circulation following cardiac arrest: an observational study. Emerg Med J. 2014 Mar 24.
- Ahn A, Yang J, Parnia S: A Pilot Study Examining the Relationship between Regional Cerebral Oxygen Saturation in the Immediate Post-resuscitation Period and Survival to Hospital Discharge.American Thoracic Society Meeting, Philadelphia, May, 2013
- Budsberg S, Shuler M, Freedman B, Hansen M. Evaluation of NIRS, serum biomarkers and muscle damage in a porcine balloon compression model of acute compartment syndrome. Fort Lauderdale, Florida August 15, 2013. Poster presentation.
- Meex I, De Deyne C, Dens J, Scheyltjens S, et al. Feasibility of absolute cerebral tissue oxygen saturation during cardiopulmonary resuscitation. Critical Care 2013;17:R36 doi:10.1186/cc12546
- Parnia S, Ahn LI, Nasir A, Golder K, et al: The Utility of Cerebral Oximetry during In-Hospital Cardiac Arrest as a Marker for the Prediction of Return of Spontaneous Circulation (ROSC). American Heart Association, Dallas, Nov. 2013
- Roskosky M, Robinson R, Shuler M, Freedman B. Subcutaneous Depth in a Traumatized Lower Extremity. Military Health System Research Symposium. Fort Lauderdale, Florida August 15, 2013. Poster presentation.
- Singer A, Ahn A, Henry M, Parnia S: Cerebral Oximetry Monitoring during CPR is Associated with Return of Spontaneous Circulation in Emergency Department Patients in Cardiac Arrest. Annual Meeting of the Society for Academic Emergency Medicine, Atlanta, May, 2013
- Wutzler A, Nee J, Boldt LH, Kuhnle Y, et al. Improvement of cerebral oxygen saturation after successful electrical cardioversion of atrial fibrillation. Published on behalf of the European Society of Cardiology. Europace Advance Access published July 31, 2013.
- Wutzler N, Otto S, Grasses L, et al. Decrease in cerebral tissue oxygenation under simulated ventricular and supraventricular tachycardia. Presented at the DIVI 2013 conference in Germany, 2013.
- Ahn A D’Orazi F Malik H Parnia S: A Pilot Study Examining the Role of Regional Cerebral Oxygen Saturation Monitoring as a Marker of Return of Spontaneous Circulation in Shockable and Non-Shockable Causes of Cardiac Arrest. American Heart Association Annual Meeting, Los Angeles, Nov. 2012
- Ahn A, Yang J, Parnia S: A Pilot Study Examining Survival and the Balance between Oxygen Delivery and Uptake in the Brain in the First 24 and 48 hours following Return of Spontaneous Circulation from Cardiac Arrest. American Heart Association Annual Meeting, Los Angeles, Nov. 2012
- Azzouz N, Yordanov Y, Kalpokdjian A, Sobotkah1J, Pourriat JL. Near-infrared spectroscopy (NIRS) for patients with minor or moderate head trauma in the ED.International Conference on Emergency Medicine. Paris, France. June 27 – 28, 2012. Poster session.
- Brown K, Singh H, Belani K, Adhikari R, Beebe D. Monitoring Normal Cerebral Oxygen Saturation: Comparison Between Three Oximeters.Midwest Anesthesia Resident’s Conference. Chicago, IL. March 17, 2012. Poster session.
- Cole A, Herman R, Heimlich J, Ahsan S, Freedman B, Shuler M. . Ability of Near Infrared Spectroscopy to Isolate Muscle Compartments of the Upper Extremity.The American Orthopaedic Association. Washington DC. June 28, 2012. Poster presentation.
- Davie SN, Grocott HP. Impact of Extracranial Contamination on Regional Cerebral Oxygen Saturation: A Comparison of Three Cerebral Oximetry Technologies.Anesthesiology. 2012;116(4):1-7.
- MacLeod D. Nonin EQUANOX Advance™ 8004CA Cerebral Oximeter Sensor Provides Valid Assessment of True Tissue Oxygen Saturation.2012. Data on file at Nonin Medical.
- Moseley B, Britton JW, Nelson C, Lee RW, So E. Periictal Cerebral Tissue Hypoxemia: A Potential Marker of SUDEP Risk.Epilepsia. 2012 Dec;53(12):e208-11
- Moseley BD, Britton JW, Nelson C, Lee RW, So E. Generalized Tonic Clonic Seizures Are Associated with Cerebral Tissue Hypoxemia. 5th Annual Neurology Science Day Poster Session, Los Angeles, CA, January 23rd, 2013.
- Moseley BD, Britton JW, Nelson C, Lee RW, So E. Generalized Tonic Clonic Seizures Are Associated with Cerebral Tissue Hypoxemia. 65th Annual Meeting of the American Academy of Neurology, San Diego, CA, March 19th, 2013.
- Nasir A, Ahn A, D’Orazi F, Malik H, Parnia S: Cerebral Perfusion Targeted Resuscitation – A Novel Method of Cardiac Arrest Resuscitation. American Heart Association Annual Meeting, Los Angeles, Nov. 2012
- Nasir A, Richman P, Parnia S: A Feasibility Study Of The Role Of Regional Cerebral Oxygen Saturation Monitoring In Predicting Neurological Outcomes Following Cardiac Arrest. American Thoracic Society Meeting, San Francisco, May 2012
- Nasir A, Richman P Parnia S: A Study Evaluating The Role Of Automated Cardiopulmonary Resuscitation In Achieving Return Of Spontaneous Circulation, Optimal Cerebral Perfusion And Neurological Outcomes In In-Hospital Cardiac Arrest. American Thoracic Society Meeting, San Francisco, May 2012
- Nasir A, Richman P, Parnia S. A Study of Regional Cerebral Oxygen Saturation Monitoring in Predicting Neurological Outcomes Following Cardiac Arrest.American Thoracic Society. San Francisco, CA. May 21, 2012. Poster session.
- Nasir A, Richman P, Parnia S. Automated Cardiopulmonary Resuscitation Improves Return of Spontaneous Circulation, Cerebral Perfusion and Neurological Outcomes in In-Hospital Cardiac Arrest.American Thoracic Society. San Francisco, CA. May 21, 2012. Poster session.
- Schwarte L, Schober P. Near-Infrared Spectroscopy (NIRS) to monitor peripheral tissue oxygenation in an airplane-based and a helicopter-based emergency medical service: A safety and feasibility study.European Congress of Trauma and Emergency Surgery. Basel, Switzerland. May 15, 2012. Poster session.
- Srikanthan JR, Singh H, Adhikari R, Beebe DS, Patterson S, Belani KG. Changes in Skeletal Muscle Oxygenation During Cyanide Toxicity.Midwest Anesthesia Resident’s Conference. Chicago, IL. March 17, 2012. Poster session.
- Walker CT. Evaluation of the EQUANOX™, FORE-SIGHT™ and INVOS® Systems at St. Francis Hospital in Columbus, GA.2012. White Paper.
- Wroblewski J, Ulrich F, Lobbestael A, Prior M. A Breakthrough Technology Using Nonin Medical’s Dynamic CompensationTM Algorithm for Neonatal/Pediatric Cerebral Oximetry.2012. Data on file at Nonin Medical.
- Bickler PE, Feiner JR, Eilers H, et al. Performance of 5 Cerebral Oximeters During Hypoxia in Healthy Volunteers. American Society of Anesthesiologists Annual Meeting. Chicago, IL. October 17, 2011. Poster session.
- Brown K, Singh H, Beebe D, et al. Monitoring Normal Cerebral Oxygen Saturation: Comparison Between Three Oximeters. The 13th Annual Robert Hebbel Department of Medicine Research Day. Minneapolis, MN. November 11, 2011. Poster Session.
- Cizenski JD, Robinson K, Hojnowski K, et al. Noninvasive regional oximetry correlates with direct Laser Doppler measurement of intestinal perfusion. FASEB J. 2011; 25: 814.21.
- Davie S, Grocott H. The impact of extra cranial contamination on NIRS measurements of regional cerebral oxygen saturation: a comparison of three different cerebral oximeters. Society of Cardiovascular Anesthesiologists 33rd Annual Meeting. Savannah, GA. May 3, 2011. Poster session.
- Davie S, Grocott H. Cerebral Oximetry: The impact Of Extracranial Contamination. Canadian Anesthesiologists’ Society. Toronto, Canada. June 27, 2011. Poster session.
- De Figueiredo L, Kramer G, Auler J, et al. Testing Smart Monitors in STARS (Sao Paulo Trauma Assessment and Resuscitation Study) – The first 24hrs of En Route Trauma Care. Advanced Technology Applications for Combat Casualty Care. Fort Lauderdale, Florida. August 15 – 18. 2011. Poster session.
- De Hert S, Jobsis M, Brevoord D, Evers V, Preckel B. Comparison of EQUANOX 7600 and INVOS 5100 cerebral oximeters in cardiac surgery patients. Society of Cardiovascular Anesthesiologists 33rd Annual Meeting. Savannah, GA. May 3, 2011. Poster session.
- Dominguez WG, Navarro LH, Lima RM, et al. Continuous NIRS Measurement Of Regional Oxygen Saturation (rS02) For Assessment Of Blood Pressure During Hemorrhagic Hypotension In A Swine Model. Shock Society’s 34th Annual Conference. Norfolk, VA. June 14, 2011.
- Frappart M, Lemoine L, Gomis P, Malinovsky J. Study of changes in cerebral oximetry by NIRS and put under general anesthesia in knee-chest position.. SFAR. Paris, France. September 21 – 24, 2011. Poster session.
- MacLeod D, Ikeda K. Nonin EQUANOX 8004CA Advance Cerebral Oximeter Sensor provides valid assessment of true tissue oxygen saturation. International Anesthesia Research Society. Vancouver, Canada. May 23, 2011. Poster session.
- MacLeod DB, Ikeda K, Lobbestael AA, Vacchiano C, Shaw AD. Influence of Arterial CO2 Tension Upon Cerebral Tissue Oxygen Saturation. American Society of Anesthesiologists Annual Meeting. Chicago, IL. October 17, 2011. Poster session.
- MacLeod DB, Ikeda K, Vacchiano C, Shaw AD. Effect of Addition of 4th Wavelength to Nonin Equanox Cerebral Oximeter. American Society of Anesthesiologists Annual Meeting. Chicago, IL. October 19, 2011. Poster session.
- Moerman A, De Hert S. Are cerebral oximeters designed to measure ambient light? Br. J. Anaesth. 2011; 106: 753 – 755.
- Neal M. The use of cerebral oximetry monitoring in the electrophysiology lab. Electrophysiology Lab Digest. 2011; 11(6): 16 – 18.
- Rebet O, Fischer MO, Gerard JL, et al. Cerebral and Peripheral rS02 Values Before and After a Fluid Challenge: A Comparative Study with Scv02. American Society of Anesthesiologists Annual Meeting. Chicago, IL. October 18, 2011. Poster session.
- Rebet O, Fischer M.O., Gerard J.L., Hanouz J.L., Fellahi J.L. rSO2 cerebral and peripheral before and after volume expansion: a comparative study with SvCO2.. SFAR. Paris, France. September 22, 2011. Poster session.
- Schober P, Christiaans HMT, Loer SA, Schwarte LA. Peripheral tissue oxygenation measurement by NIRS (near-infrared spectroscopy) using the Nonin/Equanox-7600 is not disturbed in helicopter-EMS (HEMS) environment. European Society for Trauma and Emergency Surgery. Milan, Italy. April 27, 30, 2011. Poster session.
- Schober P, Christiaans HMT, Loer SA, Schwarte LA. Peripheral tissue oxygenation measurement by NIRS (near-infrared spectroscopy) using the Nonin/Equanox-7600 is not disturbed in helicopter-EMS (HEMS) environment. European Society of Anesthesiology. Amsterdam. June 13, 2011. Poster Session.
- Shuler MS, Cole A, Robinson M, Freedman BA. Comparison Of Near Infrared Spectroscopy Values Between Compartments Of The Lower Extremities. Advanced Technology Applications for Combat Casualty Care. Fort Lauderdale, FL. August 15, 18, 2011. Poster session.
- Walker CT. Choosing a cerebral oximeter, is it really a no brainer? AACP Newsletter. Spring 2011; 10 11, 15.
- 1. MacLeod et al: ASA Annual Meeting, 2011